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微囊液體制劑凍融穩(wěn)定性試驗箱

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更新時間:2023-09-02 15:27:04瀏覽次數(shù):230次

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商鋪產(chǎn)品:1006條

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聯(lián)系人:王林

產(chǎn)品簡介

農(nóng)藥凍融穩(wěn)定性試驗箱依據(jù)NYT 2989-2016 農(nóng)藥登記產(chǎn)品規(guī)格制定規(guī)范設計制造。用于微囊液體制劑的凍融穩(wěn)定性試驗,壓縮機、加熱部分、電源控制部分均采用進口件,高質(zhì)量、高性能。

詳細介紹

一、簡介:

農(nóng)藥凍融穩(wěn)定性試驗箱依據(jù)NYT 2989-2016 農(nóng)藥登記產(chǎn)品規(guī)格制定規(guī)范設計制造。用于微囊液體制劑的凍融穩(wěn)定性試驗,壓縮機、加熱部分、電源控制部分均采用進口件,高質(zhì)量、高性能。滿載運轉(zhuǎn)時凍融箱內(nèi)各點溫度極差不超過1℃。自動控制,數(shù)據(jù)曲線實時動態(tài)顯示、試驗數(shù)據(jù)自動存儲,具有試驗意外終止自動恢復功能。

微囊液體制劑等應進行凍融穩(wěn)定性試驗。試驗目的是確保成囊制劑在溫度變化時囊的完整性,以確保有效成分完整的釋放。結(jié)凍和融化穩(wěn)定性試驗條件為在(-10±2)℃和(20±2)℃之間做4個循環(huán),每個循環(huán)為結(jié)凍18h融化6h。微囊液體制劑主要有微囊懸浮劑(CS)、微囊懸浮-水乳劑(ZW)、微囊懸浮-懸浮劑(ZC)、微囊懸浮-懸乳劑(ZE)等劑型。

1.微囊懸浮劑(CS)及微囊懸浮-懸浮劑(ZC)凍融穩(wěn)定性合格要求為:儲后游離有效成分含量、酸堿度或pH范圍、濕篩試驗、懸浮率、自發(fā)分散性、傾倒性等應符合產(chǎn)品規(guī)格要求;

2.微囊懸浮-水乳劑(ZW)及微囊懸浮-懸乳劑(ZE)凍融穩(wěn)定性合格要求為:儲后游離有效成分含量、酸堿度或pH范圍、濕篩試驗、分散穩(wěn)定性、傾倒性等應符合產(chǎn)品規(guī)格要求。

1. Introduction

The pesticide freeze-thaw stability test chamber is designed and manufactured in accordance with NYT 2989-2016 pesticide registration product specifications. It is used for freeze-thaw stability test of microcapsule liquid preparations. The compressor, heating part and power control part are all imported parts with high quality and high performance. The temperature difference of each point in the freezing and thawing box does not exceed 1℃ when operating at full load. Automatic control, real-time dynamic display of data curve, automatic storage of test data, and automatic recovery function for unexpected termination of test.

Freeze-thaw stability tests should be carried out for microencapsulated liquid preparations. The purpose of the test is to ensure the integrity of the capsule when the temperature changes in the encapsulated formulation, so as to ensure the complete release of the active ingredients. The freezing and thawing stability test conditions are 4 cycles between (-10±2)℃ and (20±2)℃, and each cycle is freezing for 18h and thawing for 6h. Microcapsule liquid preparations mainly include microcapsule suspension (CS), microcapsule suspension-water emulsion (ZW), microcapsule suspension-suspension (ZC), microcapsule suspension-suspension emulsion (ZE) and other dosage forms.

1. Qualified requirements for freeze-thaw stability of microcapsule suspension (CS) and microcapsule suspension-suspension (ZC) are: free active ingredient content after storage, pH or pH range, wet sieve test, suspension rate, spontaneous dispersion, Pourability, etc. should meet product specifications;

2. Qualified requirements for freeze-thaw stability of microcapsule suspension-water emulsion (ZW) and microcapsule suspension-suspoemulsion (ZE) are: free active ingredient content after storage, pH or pH range, wet sieve test, dispersion stability, dumping The performance should meet the product specification requirements.


二、技術(shù)參數(shù):

1、有效容積:500×500×600mm

2、外形尺寸:1350×850×1700mm

3、溫度范圍:-40℃~+80℃

4、升降溫速率:升溫速率:3℃/min

5、降溫速率:0.7~1℃/min(+80℃<->-40℃。空載,全程平均)

6、循環(huán)次數(shù):4次(任意設定)

7、凍結(jié)時間:18小時(任意設定)

8、融化時間:6小時(任意設定)

9、溫度波動度:≤±0.5℃

10、溫度均勻度:≤2℃

11、溫度偏差:≤±2℃

12、運行功率:≈3.0KW

13、凈重:150KG

2. Technical parameters

1. Effective volume: 500×500×600mm

2. Dimension: 1350 × 850 × 1700mm

3. Temperature range: -40℃~+80℃

4, ramp rate: heating rate: 3 ℃ / min

5. Cooling rate: 0.7~1℃/min (+80℃<->-40℃. No load, average throughout the whole process)

6. Number of cycles: 4 times (arbitrarily set)

7. Freezing time: 18 hours (arbitrarily set)

8. Melting time: 6 hours (arbitrarily set)

9. Temperature fluctuation: ≤±0.5℃

10. Temperature uniformity: ≤2℃

11. Temperature deviation: ≤±2℃

12. Operating power: ≈3.0KW

13. Net weight: 150KG


三、主機配置:

1、7寸TFT真彩液晶、可編程溫度控制儀

2、制冷壓縮機:法國泰康全封閉風冷,

3、PLC主模塊、溫度傳感器模塊、通訊線、以太網(wǎng)/USB延長、配件包

4、支持USB接口連接移動U盤導出歷史曲線、歷史數(shù)據(jù)、報警記錄,可用PC上位機軟件打開 U盤中導出的數(shù)據(jù)進行查看、打印、記錄

5、遠程控制

A電腦安裝上位機監(jiān)控軟件通過以太網(wǎng)口直連或者無線路器由局域網(wǎng)進行遠程監(jiān)控:

6、接口功能:接口設備支持微型打印機

7、運行模式:定值、程式運行可以選擇

8、溫濕度精度顯示調(diào)節(jié)

9、屏保、亮度可調(diào)功能

10、超溫、報警停機功能

11、溫度多點補償功能

12、 工作室:304不銹鋼板

13、外殼:優(yōu)質(zhì)冷板表面噴塑

14、帶觀察窗照明燈

Three, host configuration:

1. 7-inch TFT true color LCD, programmable temperature controller

2. Refrigeration compressor: French Taikang fully enclosed air-cooled,

3. PLC main module, temperature sensor module, communication line, Ethernet/USB extension, accessory package

4. Support the USB interface to connect to the U disk to export historical curves, historical data, and alarm records. You can open the exported data in the U disk with the PC host computer software to view, print, and record

5. Remote control

A computer installs the host computer monitoring software through the Ethernet port direct connection or the wireless router is remotely monitored by the local area network:

6. Interface function: The interface device supports micro printers

7. Operation mode: fixed value and program operation can be selected

8. Temperature and humidity accuracy display adjustment

9. Screen saver and brightness adjustable function

10. Over temperature, alarm and shutdown function

11. Temperature multi-point compensation function

12. Studio: 304 stainless steel plate

13. Shell: high-quality cold plate with plastic spray on the surface

14. Lighting lamp with observation window


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